Ashwagandha Withania somnifera Uses, Dose, Side Effects, Research

Ashwagandha – Withania somnifera is a powerful gift of nature and Ayurveda.  Talk about Ayurveda treatment for anxiety, leucoderma, depression, insomnia, weight gain, weight loss, immunity, muscle strength, body building, anti oxidants, sexual stimulant and so on. The herb does it all and more.

Botanical Name: Withania Somnifera Dunal
Family- SOLANACEAE (Kantakari Kula)

Ashwagandha For Coronavirus

Natural compounds from Ashwagandha (Withania somnifera) have emerged as a potential drug candidate against Covid-19. It is revealed in a collaborative study of DAILAB at Indian Institute of Technology (IIT) Delhi and National Institute of Advanced Industrial Science and Technology (AIST), Japan.

The researchers targeted the main SARS-CoV-2 enzyme for splitting proteins, known as the Main protease (Mpro). Mpro plays a key role in replication of the virus. The researchers have discovered that a chemical Withanone (Wi-N) – C28H38O6, derived from Ashwagandha and Caffeic Acid Phenethyl Ester (CAPE), an active ingredient of New Zealand Propolis, has the potential to block the activity of Mpro.
Withanone also potentially blocks the entry of virus through the cell membrane.
Withanone is a steroidal lactone, present in the roots of Ashwagandha. It belongs to a group of compounds called Withanolides.

Other factors that boost the importance of Ashwagandha in potential prevention of Covid 19:
Ashwagandha boosts body immunity and increases body’s natural ability to fight viruses.
It is a natural anti oxidants and is also useful in the treatment of fever and respiratory tract infections.
It is widely used to improve body strength, immunity and to relieve stress.

With all these positive points, it can be said that it is wise to include Ashwagandha in your herbal tea.

How to take Ashwagandha?
It can be made into a herbal tea. 1 Teaspoon of its root powder is added to a cup of water, boiled for 3 – 5 minutes. Filtered. This – in 50 ml dose is the adult dose.
If you wish, you can add other antiviral herbs and spices such as Guduchi, ginger, long pepper, cinnamon etc to this herbal tea mix.
Ashwagandha can also be consumed in the form of powder – 3 – 5 grams, along with milk or water.
Its capsule or tablet is also available in the market. Adult dose of 250 mg capsule or tablet is – 1 tablet once or twice a day, before or after food.

Because of its anti anxiety properties, being rich in anti oxidants and hypoglycemic activity, it is very useful in treating diabetes.
Ashwagandha is frequently used in cognitive impairment disorders and bipolar disorder. In such cases, it is made into combination with other nontropical herbs such as Gotu Kola.

Home remedies

By Dr MS Krishnamurthy MD(Ayu), PhD
Winter cherry is used in the preparation of several simple medicaments and few such recipes are mentioned here below-

To improve vigor

1. Asgandha milk for rejuvenation and promotion of vigor:
4-5 roots of Ashwagandha (5-10 gram of coarse powder can be used) are cooked well with 200 ml of milk and 400 ml of water.This is filtered and consumed when it is lukewarm. This promotes the vigor and is an established rejuvenator.

For old age tiredness

2. Aswagandha remedy for tiredness in old age:
Fine powders of
Ashwagandha
Kapikacchu – Mucuna pruriens and
Sesame seed are taken, mixed thoroughly.

It is administered in a dose of 5 grams, with a cup of warm milk.
It is useful to relieve tiredness, fatigue and geriatic problems such as arthritis.
Read related: Feeling Sleepy All The Time? 18 Reasons And Solutions As Per Ayurveda

For allergic rhinitis

3. Aswagandh for allergic rhinitis:
Equal amount of Turmeric-Ginger and winter cherry fine powders are taken mixed well. 3 grams of this mix powder is consumed early in the morning and in late evenings along with warm water or lukewarm milk, before food. This is useful to relieve allergic rhinitis.

For leucorrhoea

4. Milk processed ashwagandha root powder as rejuvenator and in leucorrhoea:
100 gram of Ashwagandha roots are selected and soaked in cow’s milk. Later it is boiled in this milk. Further it is dried under sunshine. The procedure is repeated for 7 times.

2-3 gram of this powder is taken daily along with a teaspoon of ghee. This improves reproductive health of both men and women. It is a specific remedy for leucorrhea.

To improve sperm count

5. Ashwagandha powder with ghee for low sperm count:
2-3 gram of Ashwagandha root powder is mixed with honey and ghee and taken regularly. This helps to relieve the senile debility and seminal disorders especially oligospermia.

Asgandh

Use in depression

Withania somnifera for depression:
It is widely used in treating anxiety, depression, chronic fatigue syndrome, adrenaline fatigue. Hence, it is used as an ingredient in Manasamitra vatakam and Brahmi Vati two famous Ayurveda tablets.

Use for numbness

Ashwagandha for numbness –
It improves blood circulation, a very good anti oxidant, acts as a nervine tonic and soothes nerves. Hence, it is useful to relieve numbness.

Ashwagandha for sleep

Because Ashwagandha is useful in relieving anxiety and depression and because of its nerve calming effect, it is used in treating sleep disorders.

For weight loss

Usually for weight loss, it is administered in capsule or powder form along with milk and water. it improves muscle strength, hence enables one to be more physically active, hence useful in weight loss.
It also helps to relieve depression. Many depression patients often put on weight either due to depression itself or due to anti depressant medication. In either case, Ashwagandha is useful to fight both depression and related weight gain.

For weight gain

Because it improves muscle strength and has nutritive value, when it is used along with other high nutrition foods like large quantities of ghee, milk and sugar candy, Withania somnifera is very useful to put on weight.
For this purpose, usually 3 grams of Ashwagandha powder is mixed with a teaspoon of ghee and administered at night, before food for a month time.

You say Ashwagandha and its related products can be used both for weight gain and weight loss. How? 
First thing to remember is, in Ayurveda we talk about the whole herbs and not their individual chemicals extracted. 
The same herb / Ayurvedic medicine, given in different doses, can bring about different effects. 
For example, Ashwagandha powder with ghee – is useful in targeting mental disorders, stress, infertility issues, muscle weakness, low body weight etc. This combination is useful to balance Vata very effectively, hence can be useful to gain weight. 

Whereas, Ashwagandha with honey, is more effective in balancing Kapha Dosha, hence useful in losing weight. 

In other Ashwagandha products like Ashwagandharishta, Ashwagandhadi churna, Aswagandha ghrita etc, – they can be used both for weight gain and weight loss. 

If one take these medicines in low dose – 5 – 10 gram or 10 ml per day and does good diet control and exercise, then these can improve muscle strength, reduce body stress and help in quick weight loss. 
Whereas, if they are given along with ghee, in high dose, with nourishing foods, can be useful in weight gain as well. 

For heart care

Ashwagandha is a very good  anti oxidant and acts as a heart tonic. It improves strength of muscles of heart (cardiac muscles).
It can also be useful in high BP and to relieve stress.

Muscle pain, strength, wound healing

Its external application in the form of root paste or in the form of oil (prepared in sesame oil base) is useful to relieve pain, inflammation, useful in skin diseases and in chronic non healing wounds.
its leaf or root paste is used externally to treat painful swellings, abscesses, cellulitis and sinuses.

Usage in sexual disorders

There are some studies done which proves Withania somnifera’s testosterone boosting action. (report)
It improves muscle strength, hence quite useful in treating premature ejaculation and in few cases of erectile dysfunction.
It also relieves anxiety and depression, so helps to improve sexual performance.
It is also used in treating and improving female libido.

Dry Ashwagandha root

Medicinal qualities

Withania somnifera – medicinal qualities –
Rasa (taste) – Katu (pungent), Tikta (bitter), Kashaya (astringent)
Guna (qualities) – Snigdha (oiliness, unctuousness), Laghu (lightness)
Veerya – Ushna – Hot potency
Vipaka – Katu undergoes pungent taste conversion after digestion.
Effect on Tridosha -Balances Tridosha, especially Kapha and Vata.

Part Used

Ashwagandha root, Aswagandha Leaves, Alkali

Dosage

Ashwagandha Powder 3 – 6 g in divided dose per day.
Capsule – 250 – 500 mg – once or twice a day, based on doctor’s advice.
Milk, water, yogurt, honey and ghee are a few co-drinks consumed along with Ashwagandha.
If it is ghee, mix ashwagandha powder with ghee, make a paste and swallow with a cup of hot water. Used commonly in Pitta disorders.
If it is sesame oil, mix ashwagandha powder with sesame oil, make a paste and swallow with a cup of hot water. Used commonly in Vata disorders – brain and neurological diseases, weak muscles etc.
If it is honey, mix ashwagandha powder with honey, make a paste and swallow with a cup of cold water. Always remember to use cold water while using honey.
If it is yogurt, the yogurt should not be very sour. If it is very sour, it can increase Pitta – heat in the body. Keep in mind that Ashwagandha is also slightly heat producing. Hence, this precaution.

Before food or after food?
Some people feel burning sensation if Ashwagandha is consumed before food or on empty stomach. Hence, it is best to take it, 30 minutes after food.
If Ashwagandha milk remedy is made, then it can be taken before food, based on your doctor’s advice.

Legal Substitute for ashtavarga

Ashtavarga is a group of eight herbs with very high rejuvenation and anti aging qualities. Among them,
Kakoli-Roscoea purpurea
Kshirakakoli- Lilium polyphyllum – White Himalaya Lily – these two herbs are legally substituted with Ashwagandha, because of similar qualities.

Health benefits

Withania somnifera health benefits
Balaprada, Balya – improves strength and immunity
Vaajikari – improves sexual performance, useful in premature ejaculation and in some cases of erectile dysfunction.
Vrushya – acts as aphrodisiac
Rasayani – improves life expectancy, anti aging, elixir.
Pushtiprada – improves body nourishment
Kaasam hanti – useful in cough, cold
Anilam hanti – useful in Vataja disorders – neurological and neuro-muscular disorders like paralysis
Vranaan hanti – useful to bring about quick wound healing
Shophahara – brings down inflammation
Kanduhara – relieves itching, useful in pruritis
Vishahara – anti toxic, useful in detox programs
Shvitrahara – useful in leucoderma, on internal usage and external application
Krumihara – useful in intestinal worm infestation,
Shwasahara – useful in asthma, chronic respiratory diseases
Kshatahara – useful in injury healing
Kshayahara – useful in treating muscle wasting, emaciation, post tubercular treatment to improve muscle mass and strength
Ati Shukrala – improves semen quantity and quality
It helps in reducing blood pressure on oral intake.
It is useful in relieving dysmenorrhea(painful menstruation)
It has diuretic action

Indian Ginseng

Major Chemical constituents

Withaferin A; withanone, withanolide WS-1, withanolide A to Y; somnirol, somnitol, withasomniferin A, nicotine, preudotropine, tropine, solasodine, withasomnine, Sitoindosides VII-X, sominone, Sominolide etc. (Reference: Illustrated Dravyaguna Vijnana, Vol. II, by Dr JLN Shastry)
The somniferin chemical constituent of the drug is well known for its sedative and anxiolytic effect. Due to sedative benefit the roots are used in anxiety, nervousness, fatigue, giddiness, fainting, loss of sleep etc. In case of Premature ejaculation resulted due to anxiety it has shown very significant benefit.

Ashwagandha powder

Use in auto-immune disorders

Can Ashwagandha be used in Hashimoto thyroidits? I have heard that it should not be used?
A false concept is there, that immune boosting herbs like Ashwagandha cannot be taken in auto-immune disorders. I do not approve of this concept.
Ashwagandha in Hashimoto thyroidits / hypothyroidism would effectively address to the symptoms of stress, weight gain, muscle pain, joint pains, depression etc.
The regular dose (needs approval by consulting Ayurvedic doctor) for this is – half a teaspoon (3 g) at night, with a cup of milk or water, 10 minutes after food.

For hypothyroidism

Ashwagandha – stress reliever, anti oxidant, stimulates thyroid – Decreases TSH and improves T3 and T4. – placebo-controlled study

For hyperthyroidism

It is not directly indicated in the treatment of hyperthyroidism.
But it is useful in treating below symptoms which are associated with hyperthyroidism.
Nervousness, irritability
Fatigue, muscle weakness
more frequent bowel movements
Difficulty sleeping.

For boosting immunity

Stimulate immunological activity in mice.
Enhances the total WBC count (17125 cells/mm(3)) on 10th day.
Bone marrow cellularity (27×10(6) cells/femur) as
Administration of Withania extract also showed an enhancement in phagocytic activity of peritoneal macrophages (76.5 pigmented cells/200) when compared to control (31.5/200 cells) in mice. (research)

ashwagandha plant

As immuno-modulator

  • Active paw anaphylaxis and delayed type hypersensitivity (DTH). Immunomodulatory effect was assessed.
  • A significant increase in white blood cell counts and platelet counts was observed in animals treated with Ashwagandha extract.
  • A protective effect in cyclophosphamide-induced myelo suppression was observed in animals treated with WST and WS2, revealing a significant increase in white blood cell counts and platelet counts.
  • Significant increase in hemagglutinating antibody responses and hemolytic antibody responses towards sheep red blood cells. (research)

For anxiety

Preliminary evidence suggests potent anxiolytic effects in the context of chronic stress, with lesser potency in standard forms of anxiety not related to stress. There may be more benefit to social anxiety as well with Ashwagandha relative to other anxiolytics

For high C reactive protein

The reduction seen in C-reactive protein over the course of 60 days has been noted to reach 31.6% with standard oral doses of ashwagandha supplementation.
High CRP levels can indicate that there is inflammation in the arteries of the heart, which can mean a higher risk for heart attack.

For muscle power output

Improvements in power output have been noted in trained persons subject to a sprint test and in sedentary persons who simply took the supplement as well as untrained people who began strength training.

Ashwagandha in children

Ashwagandha can be useful in children to improve growth etc. But it should only be taken if your doctor prescribes it. Without doctor’s consultation if Ashwagandha is given in children, it may lead to constipation, loose stools, abdominal cramps, drowsiness, excess sleepiness or even anxiety episodes.

If taken for immunity and health improvement, how long can it be continued?
Ashwagandha can be continued for a period of 4 – 8 weeks time.

Ashwagandha Home remedies

We have already covered a couple (and lot more to follow)
Ashwagandha remedy for easy conception for women
Boost immunity in children with Ashwagandha

Pharmacokinetics

How long does Ashwagandha stay in the body? In what ways it is eliminated out?
The effect of one dose of 500 mg of Ashwagandha capsule or tablet or 1 dose of 5 grams of Ashwagandha churna is seen for a period of 2 – 3 days. Though much pharmacokinetic data is not available, in an experimental study on rats, it was noted that extracts of Ashwagandha remained for 45–60 minutes. (half life) – 0.046% Withaferin A and 0.048% Withanolide A.
It is eliminated largely through liver, bowels and urine.

Side effects

Withania somnifera Side effects
Increased hotness, gastritis:
If used alone, for example, Ashwagandha capsule with water, it tends to worsen gastritis in people with sensitive stomach. It also causes constipation in a few.
Because of its innate hot nature, people with Pitta dominance, feel increased hotness with Ashwagandha capsule.
But if it is taken along with milk or ghee, usually this side effect is very much nullified.

Sedative effect: In a very high dose, it may have sedative effect. Hence some experts advice to avoid it during day. But I have not seen its sedative effect so big to put someone to sleep in the day time. However, it is best to take it in the day, only if your doctor has suggested so. Its sleep promotion effect can be more attributed to its anti anxiety and anti depression properties than to its sedative effect.
It can be used safely in children and lactating mother, under medical supervision.
It is best to avoid this during pregnancy.

Who should not take Ashwagandha?
It, being a Rasayana herb (anti ageing), as such there are no definitive contra-indications. Below ones are the symptoms to watch when you take Ashwagandha.

Excess body heat (give it 2–3 days to settle, if not stop)
If you take it and then develop severe anxiety or unrest (stop it and consult doc)
If it makes you drowsy ( if so, avoid it in the morning)
If it upsets your stomach (can give a try for a couple of days to see if it settles down)
If it causes diarrhea or constipation (can continue for a couple of days to see if it settles down)
If it causes Irregular heart beat (very rare)
If it lowers blood pressure / sugar excessively (stop immediately and consult doc)

Interaction with medicines, supplements

Can this be used while taking Homeopathic medicine?
Yes. This product does not react with homeopathic medicine.

Can this medicine be continued while taking supplements like multivitamin tablets, Omega 3 fatty acids etc?
Yes. Generally, this product goes well with most of the dietary supplements. However, if you are taking more than one product per day, please consult your doctor for an opinion.

With western medicines
Seek your doctor’s advice if you are taking this product along with other western (allopathic / modern) medicines. Some Ayurvedic herbs can interact with modern medicine.
If both Ayurvedic and allopathic medicines are advised together, then it is best to take Allopathic medicine first, wait for 30 minutes and then take the Ayurvedic medicine.

Ayurvedic medicines

Ayurvedic medicines with ashwagandha ingredient:
It is an important ingredient in the making of chyawanprash
Ajaswagandhadi lehyam and Ashwagandhadi Leha is a non veg and vegetarian versions – in Avaleha (lickable) form, used pretty much for similar purposes.
Ashwagandharishta is widely used in treating fainting disorder, mental fatigue etc.
Balaswagandhadi thailam

Time taken to show results

How long does Aswagandha take to show results?
It depends on the purpose of your usage.
As an anti ageing herb, Ashwaganadha is given in low doses for a few months time. So, it takes several months to bring about this action, gradually.
As an anti depressant, anti stress and sleep aid, usually Ashwagandha starts showing results in about 7 days time.
As an energy boosting herb, it starts showing results in about 3 – 5 days time.
For weight gain, it may take 1–2 months time
As a sexual stimulant, it may take about a week time to show good results. 

Research on Withania somnifera

Anti stress activity:
To evaluate the anti-stress effects of Withania somnifera, an alcoholic extract from roots & seeds dissolved in normal saline was given (100mg/kg intra peritoneal as a single dose) to 20-25 g mice in a swimming performance test in water at 28’-30’ C. It is seen that the extracts approximately double the swimming time when compared to control. It suggested that Withania somnifera induced a stage of nonspecific increased resistance during stress. Glycosides of Withania somnifera exhibited significant anti stress activity in forced swimming induced immobility in mice, restraint stress induced gastric ulcer & auto analgesia in rats. Further clinical studies should be conducted as well as studies in multiple animal based models using a variety of suitable biochemical markers to understand its mechanism of action.
Inhibition of mammary cancer metastasis:
Withaferin A showed dose-dependent inhibition of tumor growth and metastatic lung nodule formation with minimal systemic toxicity.

Hypotensive activity:
The main objective of the study was to analyze the efficacy of Ashwagandha root powder with water and with milk in treatment of hypertension. The experiment was conducted on 51 stress-oriented hypertensive subjects in the age group of 40 to 70 years. Subjects were divided into group I and group II. Supplementation of 2gm of Ashwagandha root powder was given to group I and group II with milk and water respectively in morning. Blood pressure was also recorded over a period of three months. Overall decrease in systolic blood pressure was found though it was non- significant. Further, decrease in systolic blood pressure was significant in group I, whereas decrease in diastolic blood pressure was significant in both the groups. Hence, supplementation of Ashwagandha with milk is recommended in treatment of stress- oriented hypertension

Uses as per research

Ashwagandha Uses documented as per research

  • Diabetes – reduces sugar, anti oxidant, relieves stress
  • High cholesterol – reduces bad cholesterol, anti oxidant,
  • Male infertility – improve sperm quality in infertile men.
  • Arthritis – There is preliminary research that ashwagandha taken in a particular supplement (Articulin-F) along with other ingredients might improve arthritis symptoms.
  • Parkinson’s disease. research suggests that a combination of herbs including ashwagandha improves Parkinson’s symptoms.
  • Tumors and cancer
  • Tuberculosis – relieves muscle wasting, weight loss
  • Liver problems (hepato-protective) – Gentamicin Intoxicated Rats – animal study
  • Swelling (inflammation).
  • Ulcerations – non healing wounds, abscess
  • Stress.
  • Altering immune system function.
  • Anti ageing
  • Fibromyalgia – body ache

Ashwagandha churna Vs capsule

Ashwagandha churna Vs Ashwagandha capsule
When pure uncontaminated Ashwagandha churna is available, then it is usually preferred to capsule form. But usually Churnas get contaminated easily.
When Ashwagandha needs to be formulated as a mix powder along with other powders (such as Ashwagandhadi Churna, used in indigestion), powder form has advantage over the capsule form.
Ashwagandha capsule is usually prepared with its water extract or crude extract, which retains most of its chemical constituents.
When it comes to easy dosage fixing and easy consumption, capsule is lot better than Churna form, because of bitter taste of Ashwagandha and powder dose fixing is a bit difficult task.
If Ashwagandha alone is to be used for treatment, then capsule can be preferred. But if used alone with water, it tends to cause burning sensation in stomach, hence it is advisable to use it along with milk or ghee, or a combination of both.

Administration in Ama condition

Q: I was taught not to give it in ama conditions, or Kapha vikruti, and that agni needs to be strong when taking Ashwagandha lehyam.

  • Ashwagandha is Ushna veerya – hot -> Agni promotion. So, Ashwagandha alone is good to use in such a condition, in the form of powder, capsule or tablet.
  • Ashwagandhadi Lehyam contains jaggery etc that are heavy to digest ingredients -> So, avoid it if you have low Agni (digestion strength).

Does Ashwagandha for anxiety cause addiction?

Q: I took Ashwagandha capsule for 10 days. I missed on the 11th day and felt anxiety. Will I be dependant on Ashwagandha forever? 
Usually Ashwagandha is advised for at least 24 – 6 weeks. After that, gradually the dose is reduced and stopped over a period of 2 – 3 months time.
In your case, I would advice to take Ashwagandha capsule – 1 capsule at night after food for 1 month continuously. For the second month, take it on alternate days for next 4 – 6 weeks and then finally stop it.
It is not habit forming. Meaning, it will nto cause you to stay addicted to Ashwagandha.

Ashwgandha with milk

Ashwagandha with milk is a very good combination. There is a dosage form called Ksheerapaka, in which these two are cooked together. This combination can be taken in all seasons. Hotness of Ashwagandha nullifies the coldness of milk. This combination makes the milk more digestible.

Ashwagandha with Amla

Both Ashwagandha and amla are potential ingredients in ayurveda which is used in the preparation of several formulation. Both these have a wide range of actions on the body. Thus its action on the body varies between individuals.
Here it is to be noted that Amla juice can be taken on daily basis as the constitution easily suits with the internal body system at its best. Ashwagandha on the other hand is powerful in action and hence it shall be used only for a limited period of time.
Basically Ashwagandha is used to relieve stress and secondly as an aphrodisiac. Most of the formulations in Ayurveda which is meant for treating mental conditions have ashwagandha as one of the prime ingredients. When used as an aphrodisiac it shall be used by those above 23 years of age as on an average it is only after this age that means body becomes suitable enough to handle the action of ashwagandha. When both Ashwagandha and amla are used together, ashwagandha acts as a chief ingredient and amla acts as a medium and catalyst in enhancing the action of ashwagandha.

Test for purity

How to know if Ashwagandha is genuine?
If you buy it from a reputed brand, there is no need to worry about its quality. I
There are no tests that can be done at home to prove the authenticity of the product.
f you have purchased it and unsure, then send the sample to a nearby analysis laboratory to test for purity and identity. 

Addison’s disease

Addison’s disease is a disorder of the hormonal system. It is caused due to failure of adrenal glands to produce normal amounts of cortisol and aldosterone hormones.
Though there is no definitive role of Ashwagandha, established in curing the Addison’s disease, it is very useful to improve many symptoms of the disease such as fatigue, muscle weakness, lack of strength, loss of appetite, weight loss, etc.

Distribution

Distribution of Withania somnifera:
Throughout the dry and subtropical India. It is also cultivated extensively throughout India at present.
Ashwagandha plant can easily survive and grow in almost all parts of South India.

Sanskrit synonyms

Hayagandha, Turagnagandha, Vajigandha, Ashwagandha – Ashwa, Haya, Vaji means horse and gandha means smell. This plant smells quite like horse dung.
Gatrakari – Gatra means body. It helps to improve body mass and strength
Turagi, Vajikari – Vaji means horse. This herb is used to improve sexual performance like that of a horse.
Balya- it improves strength
Varahakarni – Varaha means pig. Karna means ear. Its leaf looks similar to ear of pig.
Kushtagandhi, Pivari

Classical Categorization

Charaka-
Balya – group of herbs to improve strength and immunity
Brimhaneeya – group of herbs to improve body mass, nourishment

Varieties

There are two plants available in the trade namely
Withania somnifera (more commonly used in the name of Aswagandha)
and Withania coagulans.
The former one is denoted as Pennerugadda while the later is known as Dommadolugadda in Telugu.
There is another herb described in dhanvantari nighantu along with Ashwagandha with the synonyms like Medasvi, sthoulyadhyava, Bali, Mamsi, and Rukmini. This is considered as the big variety of Ashwagandha (W. coagulans ) by Sri Singaraja Kama Sastry (1932). The cultivated variety of Asvagandha which is thin and lean is mainly brought from nagori dist. Of Madhya Pradesh. Hence, the name “Nagori Variety”. (Reference: Illustrated Dravyaguna Vijnana Vol. II, by Dr JLN Shastry)

Vernacular Names

Hindi name- Asgandha, Asgandh
Telugu Name- Penneru Gadda/ Dommadolu Gadda
Tamil Name- Amukura, Askulang
Malayalam name – Amukkura
Marathi name – Asandh, Doragunj
Gujarathi Name – Aasandha, Ghoda Aakun
Bengali Name- Asvagandha
Kannada Name- Ashvagandhi

135 thoughts on “Ashwagandha Withania somnifera Uses, Dose, Side Effects, Research”

  1. Can Ashwagandha be taken for anxiety along with SNRI medicines, Tricyclic antidepressants and beta-blockers ?

    Reply
    • Sir,after taking ashwagandharishta i feel uneasiness in head …bt i want to continue with ashwagandharist…as it has mny health benefits…what should I do now?

      Reply
    • Its action is more on Mamsa (Muscles), Meda (Fat), Asthi (Bones), Majja (marrow) and Shukra (reproductive system) Dhatus.

      Reply
      • Hi,
        1. Ashwagandha powder – half a teaspoon after workout along with half a cup of milk (or water) can be taken anyone as a general supplement for 3 months, then give a gap of a month and continue again.
        I am not a fan of continuing any medicine / herb for a long periods of time without gaps in between, for about one year.

        2. Consider a few side effects as explained in the article. If you do not fall in those categories, then you can take it freely.
        3. For good quality organic Ashwagandha powder, please contact my brother in law – Shashi Kumar – [email protected]

        Reply
  2. Thanks for this article Dr. Hebbar. Does Ashwagandha help the thyroid function? It would be nice if you could elaborate on thyroid disease and its treatment options in Ayurveda.

    Reply
  3. Hi, very good article, but I’m still unclear out the effects of Ashwagandha on my weight. I definitely do not want to gain any more weight. I need to lose. Will this herb cause weight gain all by itself? Or does it need to be used a certain way for that to happen? Any help you can give is appreciated.

    Reply
    • Hi, if you take Ashwagandha in a low dose of one capsule or per day, for a period of not more than 2 months, then it will not cause weight gain by itself. If it is taken on a higher dose or for longer period of time, or along with other herb / herbal combinations, then it can contribute to weight gain.

      Reply
  4. Thank you Doctor for the invaluable article. I am learning a lot from your website. I really appreciate your effort.

    I have a question for you Dr.

    I notice some weight gain after taking ashwagandha with milk. Is there a better alternative for Ashwagandha?

    Thanks Dr.

    Namaste!

    Reply
  5. Hi, I surrer from anxiety and depression but I am not taking any mediaction for this. I have been advised to take liquid withania (in alcohol). Is it safe to take and is it likely to make my anxiety any worse?
    Thanks

    Reply
      • Some patients observe worsening of gastritis with Ashwagandha. Such people can take it along with milk, 30 minutes after food.

        Reply
  6. DR. I have chronic gastritis.Will it help gastritis or cause it more?.Should I avoid aswagandha for that reason even though it suppose to help thyriod?.
    If taken longer term can it cause weight gain ?.Also aswagandha consider a night shade family.

    Reply
  7. I am having Hypertension and taking valsartin tablets 80 mg from 3 months. Please tell is it safe for me to have ajaswandha leham? I read that this should not be taken by hypertensive .is it true?

    Reply
  8. Dr. I have used Amrita Ashwaganda tablets(each contains 850 mg) twice a day morning(after breakfast) and evening(around 5pm) along with milk.After using 4 days I am suffer from dehydration and my mouth became dry and drinking more water. I reduced to 1 tablet (each contains 850 mg) per day, but no use ,feeling dehydration still. Now I have stopped.Now its Ok. But I want to use this medicine because it is useful for muscle strength ,anti aging etc. Please suggest me better way of using this medicine without dehydration.
    I came to know that this medicine will use get problem like Thyroid effect , liver effect.

    Thanks&Regards
    Satheesh

    Reply
    • Hi, please use the tablet, 10 minutes after food at night only for a week. If you get the aforementioned side effects again, please stop it and consult your doctor directly. Regards.

      Reply
  9. Hi Doc,I am 25 yr male,weighing 50 kgs,i feel loss of energy most of the day beside i have high acidity and constipation problem at most times,is it safe for me to take ashwagandha..if it is,how much dosage do u suggest..?thanks

    Reply
    • Sir would advise you to take medicines for High acidity and constipation and then start of with taking Ashwagandha.

      Reply
    • Dear Madam,
      Ashwagandha indirectly can influence HGH (Human growth hormones) which is significantly responsible for growth of height. In the transition age period of 16-18 human body requires proteins and vitamins for the development of the height and weight in a balanced way. Ashwagandha helps the body in the appropriate and overall development. Regular consumption helps in growth of body height and weight and also improves body energy.

      Reply
  10. Hello Dr Hebbar ,

    I must say what an excellent trials you have made to help us over Ayurvedic medicines – its my ill fate that My grand father was also an Ayurvedic doctor but that knowledge never got transferred to us any how thank you so much for all the good work you are doing

    – I was told that Ashwagandha will help in improving Female Fertility disorders – I just need to know if Ashwagandha Leyhm can be taken by females to improve chances of conception –

    I am against Alopathy owing to the side effects and hence decided to use only Ayurvedic medicine in way trying to get back to the Rich old indian Knowledge
    Please help and Advise

    Regards
    Aditya

    Reply
    • Dear Aditya,
      Thanks for your kind words of appreciation. As they say, it is never too late to learn and adopt Ayurveda. 🙂

      Reply
  11. Dear sir, As we all are genetically different with different constitutions and patterns, we respond to treatments in many different ways. Hence Standard Ayurvedic Treatments are always individually formulated. For specific treatment, always consult with a qualified Ayurvedic physician.

    Reply
    • Dear Madam, Ashwagandha indirectly can influence HGH (Human growth hormones) which is significantly responsible for growth of height. In the transition age period of 16-18 human body requires proteins and vitamins for the development of the height and weight in a balanced way. Ashwagandha helps the body in the appropriate and overall development. So at this age it is difficult for the increase in height.

      Reply
  12. Namskar doctor sahab kya aswagandha churn aur capsule me kuch antar hai aur suxual weakness me koun jyada asarkarak hai..churn aur capsule dono me se koun sa lena chahiye (i am u
    sing patanjali product) plz bataye hindi me..

    Reply
    • Aswagandha churna le sakte he aap. Agar taklif hoti he churna khane me to capsule bhi kha sakte he.

      Reply
  13. Dear Dr.,

    Many westerners classify Ashwagandha herb as nightshade along with other nightshade vegetables such as Brinjal, etc. This is contradicting to Ayurvedic classification. For example, for diseases such as migraine, myalgia, where nightshades are not allowed and it helps also and even you have given your kind advise on the same guidelines.

    So say Ashwagandharishta, Ashwagandhadhi lehyam or even Dhanvantharam Kashayam all have Ashwagandha and their target diseases are infact towards curing nervous disorders thereby reducing pain and depression.

    Can you please clarify?

    Regards
    Vinay

    Reply
    • Dear Vinay, used part of Ashwagandha is it’s root. So it, being.nightshade or not, doesn’t matter.

      Reply
  14. Hi,
    Its fruit seed powder – in a dose of – half a teaspoon at night with a cup of hot milk for 2 months time.

    Reply
  15. Dear Mr Ramesh, as per my experience and patient reviews, Ashwagandha causes increase of heart rate.
    There is a theory that Ashwagandha should not be used in Rheumatoid arthritis at RA is a auto immune disorder and Ashwagandha would increase immunity and make it worse.
    I personally do not use Ashwagandha while treating RA. I would choose herbs like Guggulu, Sallaki, Guduchi etc.
    As per my experience, Ashwagandha increases thyroid hormone secretion.

    Reply
  16. hi Sir, muje thyroid hai (medicine band karne par thyroid badh jata hai) , aur main weight bh kum karna chahti hu ,tho kya main Ashwagandha start kar sakti hu pls dose bataiye weight kum karne k liye and tyroid control karne ke liye.

    Reply
    • Aap Giloy Satva – 500 mg per day le Sakte hai. Zyada jaankaari ke liye Ayurvedic doctor ko consult kare.

      Reply
  17. Question. My daughter is a young athlete, high level for her age. She’s 11 years & 5 months old right now. Is it safe for her to take the Ashwagandha Organic Root Powder? No side effects? Thank you.

    Reply
  18. Namaste Sir, You will need a advice from a doctor for it. Seeing BMI, constitution and prakruthi etc., the dosage will be fixed.

    Reply
  19. Hello Sir, Ashwagandha is hot in potency, sweet in post digestive effect, bitter, sweet and astringent in nature. As it is Hot in potency, it may increase in Summer. Hence, should be avoided in summer.

    Reply
  20. There is no restriction on any fruits while taking Ashwagandha + Shatavari along with milk. Just take care not to mix any sour fruits along with milk.

    Reply
  21. Hi doctor, thanks for this informative article about aswagandha.
    I have read that aswagandha is an adaptogen, i.e., it balances out the levels of hormones rather than unilaterally increasing or decreasing individual hormones, especially with respect to estrogen, progesterone and testosterone… Is this true? And if so, would it be helpful in hormone imbalance states such as hormonal acne?
    Thankyou

    Reply
    • It is very true. For the same reason, it is very useful in the treatment of hypothyroidism and as well as hyperthyroidism, in cases of PCOS etc. It is beneficial in hormonal acne.

      But while using Ashwagandha capsule, we need to watch the patient after a month to see the effect and decide on continuing.

      Reply
  22. Hi, you can take ashwagandha in the morning.
    For people seeking weight gain, long term use of Triphala is not recommended.

    Reply
  23. Sir, Is there any other ayurvedic medicine(other than ashwagandha) for GAD ( Generalized Anxiety Disorder) ?

    Reply
  24. Hi my bp always remains at 100/62. I do regular gym and weight training for 21/2 hrs and take protein supplement. I also take 4 gms of ashwagandha and 3 gms of gokhru powder with lukewarm water at bed times. Pls suggest that the low bp is due to ashwagandha and gokhru

    Reply
  25. Having weak immune system urge to motion after having milk products can take ashwagandha capsule age 46 also taking medicine for high BP. ..

    Reply
  26. Sir, i took geriforte capsule 2 per dayfor anxiety. But after 2 day onwsrds i left with complete sleep less nights untill i stop.I strongly believe its because of aswagandha. Is nutmeg in drakshasava do the sameif i take it fo anxiety???

    Reply
  27. Hi, you can take the lehyam at night. You can have barley powder or milk to reduce heat.

    Reply
  28. Dear Sir,
    I am an 18 old boy, I have been suggested Ashwagandha tablets for increasing height. I take a tablet every night before sleeping, but it causes loose motions in the morning and has also caused pimples on my face (they were absent before I started taking the medicine). Should I continue? Will the side effects subside on their own?
    Kindly help.

    Reply
  29. Hi, I work night shifts so I sleep in morning. Shall I take Ashwagandha at night or morning ? Becasue I have to stay awake all the night during work.
    Also I have started taking this recenly and my body heat is increasing, any remedies for this ?

    Reply
  30. Can you please tell me if you would recommend Ashwagandha for Alheimer’s? What have you seen as results? What dose is recommended?

    Reply
    • I have not treated any cases of Alzheimer’s successfully. I would bet more on Brahmi ghrita and Saraswatarishta than Ashwagandha.

      Reply
  31. Dear Dr,

    I want to try Ashwagandha for weight gain, to have relief from fatigue & insomnia. Is it advisable to take Ashwagandha in the morning? If so,will it cause drowsiness & affect my work. I purchased Ashwagandha capsules, each capsule contains 850mg. Is 850mg a higher dose or should I go for a lower dose
    pls advise.

    Reply
  32. My daughter suffers from anxiety and depression related to PTSD. She is 6 years of age. Would it be safe for her to take this root, and if so, how much?

    Reply
  33. Hello Doctor! Daughter’s pediatrician said it cannot be taken by the kids younger than 18y.o. Why do you think she has such opinion? Thank you

    Reply
  34. Question to :Dr J V Hebbar MD

    Due to adverse side effects of Flomax and Avodart ,I have started using Himplasia (Himalaya) tablets for my BHP, Is it also advisable to use Ashwagandha capsules, and at what dosage.?

    I am 62 years.

    Kindly reply to my email address.

    Thanks.

    Reply
  35. hello,
    after taking ashavganda capsules for 2 days i feel severe pain in stomach and the unberable pain stayed for about 6 hours and also feeling of vomiting and then i stopped taking it, what should i do now, stop taking it or any other solution?
    Thanks

    Reply
  36. 450 mg tablet, 1 at night, after food with half a cup of water or warm milk, for 6 weeks time.
    When I grow to your age, I would aim to be as physically active as you are. 🙂

    Reply
  37. Hi, as per my knowledge, nagori ashwagandha is same as plain one.
    1 gram with a cup of milk at night after food for 1 month

    Reply
  38. Hello Sir,

    Why is the dosage in capsules less i.e
    250mg whereas dosage of powder is 2-3g. Which is the best form to have this medicine.

    Regards
    Neeraj

    Reply
  39. Hello sir i want to take ashvagandha for weight gain and energy how much tablets should i take per day thank you

    Reply
  40. I am 23 yrs old and am doing regular cardio for weight loss n am taking Ashwagandha and Shilajit capsules in morning after breakfast and at night after food . Is this good to take this combo for weight loss ? …… Sir ,can women take Ashwagandha capsules ?

    Reply
  41. Ashwagandha – just 1 capsule at night after food for only 2 months time.
    You can take Hamdard safi blood purifier along with Ashwagandha.

    Reply
  42. Ihave taken one tablet of ashvagandha for last night and i got loose motion…it was as same as last time i took it…please tell me sir

    Reply
  43. Ashwagandha can be taken by below 25 year people as well.
    Do not over dose. Take only 1 capsule per day for 2 months and then stop.

    Reply
  44. I am taking Aswagandha in milk but getting constipation stomach pain can u suggest how to take and get releif from this problem.

    Reply
  45. Ashwagandha roots (Withania Somnifera) are Mainly cultivated in Neemuch District of Madhya Pradesh, India.
    Neemuch is the Only Auction Centre and Market of Ashwagandha in India.
    Kuth Meetha – Nagori Ashwagandha is also Available with traders there.
    You can get many Qualities of Ashwagandha as per Rates from Neemuch, along with any other parts of ashwagandha Plant.

    Reply
  46. I m 19 yr can ashwgandha increase my height my height is 5.6 and I prefer zym daily and 62 kg weight in me

    Reply
  47. I have recently been diagnosed tht I have sub clinical hypothyroidism
    Hvnt taken any medication
    Can only Ashwagandha help me?
    M also trying to convince.

    Reply
  48. Sir, if anybody is trying to get over his depression and anxiety then whether asvagandha would be useful or not and for how many days it must be taken if consumed at night.

    Reply
  49. Good day Dr,
    I have bought some Aswagandha extract 125mg capsules to take for anxiety and I also have really bad cronic insomnia. Can you please tell me how much to take of this to see some improvement in my health, especially sleep. My doctor has prescribed Mirtazapine antidepressant for sleep which I am scared to take will Aswagandha.
    Please advise

    Thankyou for your time

    Reply
  50. The combination is good. I would decrease Giloy Sat to 10 grams only.
    The combination is good to improve immunity, heart health and to keep fever and allergy away.
    Ayurvedic and homeopathic medicines can be taken together.

    Reply
  51. I heard ashwagandha should increase ojas, is this true? I ask because you say post digestive it is pungent and not sweet. Also can you use it everyday?

    Reply
    • Hi, Many post digestive pungents can still increase Ojas, like Ashwagandha. It is good to continue it for 2 months, then give a month gap and then continue again for 2 months and so on.

      Reply
  52. sir I would like to know if you only took ashwagandha within time will it balance all the hormones in the body also is this a drug that will bring back the fullness to the body thank you in advance

    Reply
  53. Hello sir . I have anxiety with physical symptoms like head neck numbness ,breathing problem,left side breast (near armpit)pain ,shoulder joint pain..all this was happened with me 6 months ago at that tym I took treatment from neurologist and I got relief but from now again I am having these symptoms again and I dnt want to take those allopathic drugs again please tell me some natural herbs .

    Reply
  54. sir I have read that ashwagandha should not be taken if you have Ama or congestion. How do you feel about that? I ask because ashwagandha is light and heating it also is bitter, pungent, an astringent which I would think would be good at reducing. Thank you

    Reply
  55. Hi sir. Im having sleeping problem ever since i force my self to stay awake at night to take care of my sick daughter. Now Im trying to get back my sleep. At first I took 250mg x2 capsules of Aswaganda at about 9.30 pm but it only make me drowsy till 4.30 am only than i slept a little while. Again i try to change the dosage and timing which i took 250 mg at 2.30 pm and another 250 mg at 7.30 pm after dinner. I still hv the same effect like it make me calm till midnight and I only feel like sleeping at about 4.30 am. I want your advice on this as i really want to get back my sleep which I hv lost in about 1 and a half months now. Is it ok to take the capsule in the morning in order for it to work right at night for me to hv a proper sleep. I cant visit an ayuvedic dr here in Malaysia. Its far away from my home. I really need your advice. Pls help me. Thank you sir. God bless.

    Reply
  56. Thank you Dr Hebbar garu for providing excellent article on Ashwagandha, great information about it.

    Reply

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