Persistent Depressive Disorder Symptoms, Treatment, Ayurveda Concept

By Dr Raghuram Y.S. MD (Ay) & Dr Manasa, B.A.M.S
Persistent depressive disorder is a kind of chronic depression. It is abbreviated as PDD. It is said to be a combo of 2 conditions i.e. chronic major depressive disorder and dysthymia. Dysthymia is also mentioned to be synonymous with PDD.

The symptoms of PDD are almost similar to other types of depression and people may experience feelings of deep sadness and hopelessness. These symptoms may persist for many years in PDD in comparison to other forms of depression. This also differentiates PDD from other forms of depression. This condition due to its longer persistence will interfere with ones functioning in school and work and also will meddle into personal relationships. PDD may be treated effectively by administering a combination of medications and therapies.
Read – Depression Causes, Ayurvedic Treatment, Tips And Remedies


The symptoms are similar to those of depression. The difference is PDD runs through a chronic course. The symptoms of this variant occurs on most days of the year and persist for at least for 2 years though it may persist for more than 2 years.

The symptoms listed in DSM-5 (published by American Psychiatric Association) are used by the physicians to diagnose PDD. These symptoms are –

Causes of Persistent Depressive Disorder

Since depression is common it can occur in anyone at any time. The actual causes of PDD are not known clearly. Some of the below mentioned factors might be causal of PDD –

  • brain trauma (concussion)
  • traumatic / stressful life events
  • nervous imbalances

Risk factors

A combination of biological and circumstantial factors can become risk factors and increase the risk of developing PDD. The below mentioned are included as risk factors –

  • family history of PDD or depression
  • history of other mental health disorders (anxiety, bipolar disorder etc)
  • drug use / substance abuse
  • chronic physical ailments (diabetes, heart diseases etc)

It is also found that about 21% people with substance abuse disorder also have depression which might lead to development of PDD.
Read – Effective Ayurvedic Treatment Protocol For Depression


Thorough physical examination
Blood tests or laboratory tests to rule out certain medical conditions
Referred to a mental health professional for further evaluation of mental health and its treatment.

For a diagnosis of PDD to be made one should have symptoms of the disease for 2 or more years, nearly every day of these years. This rule holds good for adults. In case of children or teens, they should have experienced a depressed mood or irritability for most of the day, nearly every day for at least 1 year.

Methodical interrogation also help in diagnosing or ruling out other mental health disorders
Read – Depression, Suicidal Tendency: Case Study, Counselling

Treatment for Persistent Depressive Disorder

Medications – Antidepressants

  • SSRI (Selective Serotonin Reuptake Inhibitors) – sertraline, fluoxetine etc
  • TCA (Tricyclic Antidepressants) – amoxapine, amitriptyline etc
  • SNRI (Serotonin & Norepinephrine Reuptake Inhibitors) – duloxetine, desvenlafaxine etc

Do not stop taking medications without your doctor’s consent. If you do so you might suffer from withdrawal symptoms and the symptoms of depression might become worse.

Psychotherapy / talk therapy is also called CBT i.e. cognitive behavioural therapy.

This therapy focuses on your actions, behaviours, thoughts and emotions and provides ways of balancing them. You will also speak to the mental health experts who will help you in knowing and accepting your symptoms and will also help in finding out safe coping habits for PDD. This therapy plays a vital role in helping you in combating symptoms and also reduce risk of future relapses.

This will also help you to –

  • express your feelings and thoughts properly and with confidence
  • adjust with the life crisis and challenges
  • replace negative beliefs / thoughts with positive thoughts
  • cope up with emotions
  • set realistic goals to self
  • identify triggering / aggravating thoughts, behaviors and emotions
  • regain sense of satisfaction
  • regain control over your life
    Read – Counselling – Types, Benefits, Myths And Facts

Lifestyle Changes

Making adjustments in one’s lifestyle can help in complementing the treatment and also to combat the symptoms with ease. Important lifestyle changes which you need to include along with your treatment plan up are –


In a study to figure out helpful and hindering factors for remission from dysthymia and panic disorder at 9-year follow up, a general model for recovery from dysthymia and panic disorders was proposed. This involved understanding self and illness mechanisms, enhanced flexibility of thinking and change from avoidance coping to approach coping. (Read more)

Another study established a temporal relationship between dysthymia and TMD i.e. temporomandibular disorder. (Read more)

Another study ‘Psychological impact of dysthymia – A study among married patients’ showed that dysthymia had considerable adverse psychosocial impact in terms of QOL, functioning (disability), social support and marital adjustment. (Read more)

A study ‘Primary dysthymia – A study of several psychosocial, endocrine and immune correlates’ showed that the altered NK cells in dysthymic patients were not related to the increased stress perception and altered coping which characterize these patients. (Read more)

Ayurveda Concept

Dysthymia is also a depression which stays for a longer period. Depression is often compared to the below mentioned conditions –

  • avasada
  • mano avasada
  • unmada / bhutonmada
  • kapha avrita pitta
  • kapha avrita vata

The same is true for dysthymia and all other variants of depression. Treatment of dysthymia also follows the line of treatment mentioned for one of these conditions and depends on how this condition is diagnosed in terms of Ayurveda.

Click to Consult Dr Raghuram Y.S. MD (Ayu)

Leave a reply

Your email address will not be published. Required fields are marked

Easy Ayurveda Video Classes

Buy Online Video Courses

Buy Easy Ayurveda Books


error: Alert: Content is protected !!